ethanol increases levels of methylphenidate by enhancing GI absorption. Dosing recommendations are based on current dose regimen and clinical judgment. benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. Contraindicated. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Additive vasospasm; risk of hypertension. Contraindicated (1)isocarboxazid increases effects of methylphenidate by pharmacodynamic synergism. Contraindicated. Monitor BP. and formulary information changes. prochlorperazine, methylphenidate. Methylphenidate may diminish antihypertensive effects. Methylphenidate may diminish antihypertensive effects. Mechanism: unknown. Potential for additive CNS stimulation. methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. . Risk of acute hypertensive episode. Monitor BP. Contraindicated (1)benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Monitor BP. calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Contraindicated. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Monitor BP. methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor Closely (1)methylphenidate will decrease the level or effect of isradipine by pharmacodynamic antagonism. Additive vasospasm; risk of hypertension. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Use Caution/Monitor. Monitor BP. Modify Therapy/Monitor Closely. Monitor Closely (2)lurasidone, methylphenidate. Monitor Closely (1)methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Share cases and questions with Physicians on Medscape consult. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Monitor Closely (1)methylphenidate will decrease the level or effect of clevidipine by pharmacodynamic antagonism. Contraindicated. Monitor Closely (2)famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Contraindicated (1)phendimetrazine increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Mechanism: pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)methylphenidate will increase the level or effect of atomoxetine by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of telmisartan by pharmacodynamic antagonism. lurasidone, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Mechanism: unknown. Contraindicated. Avoid or Use Alternate Drug. carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. dexfenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Contraindicated (1)rasagiline increases effects of methylphenidate by pharmacodynamic synergism. Most Monitor Closely (1)methylphenidate will increase the level or effect of phenytoin by unknown mechanism. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Use Caution/Monitor. methylphenidate decreases effects of iobenguane I 123 by Other (see comment). Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. only.trifluoperazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Monitor Closely (1)metaproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Monitor Closely (1)methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Monitor Closely (1)clomipramine, methylphenidate. formoterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. amitriptyline, methylphenidate. Monitor BP. only. Either increases effects of the other by pharmacodynamic synergism. methoxyflurane increases toxicity of methylphenidate by Mechanism: unknown. Monitor Closely (1)fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. hydrocodone, methylphenidate. Mechanism: pharmacodynamic synergism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Modify Therapy/Monitor Closely. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Other (see comment). Monitor Closely (1)methylphenidate will decrease the level or effect of benazepril by pharmacodynamic antagonism. Use Caution/Monitor. Serious - Use Alternative (1)ergotamine, methylphenidate. Contraindicated. Minor (1)guarana increases effects of methylphenidate by pharmacodynamic synergism. Risk of acute hypertensive episode. Mechanism: pharmacodynamic synergism. amantadine, methylphenidate. methylphenidate will decrease the level or effect of clevidipine by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor BP. Use Caution/Monitor. Use Caution/Monitor. Dosing (usual): Treatment of ADHD in children and adolescents up to 70 kg body weight. Access your plan list on any device mobile or desktop. Applies only to extended release formulation. Minor/Significance Unknown. Methylphenidate may diminish antihypertensive effects. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Desflurane. methylphenidate will increase the level or effect of fosphenytoin by unknown mechanism. Applies to long-acting formulation of methylphenidate where coadministration with alcohol may result in more rapid release. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of lisinopril by pharmacodynamic antagonism. Use Caution/Monitor. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Minor (1)amantadine, methylphenidate. Monitor Closely (1)iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. ibuprofen/famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Monitor Closely (1)methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. Risk of acute hypertensive episode. Applies only to extended release formulation famotidine decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (2)fluphenazine, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Mechanism: pharmacodynamic synergism. Monitor BP. Avoid or Use Alternate Drug. Refer to medication chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical pearls, . Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. ropinirole, methylphenidate. Use Caution/Monitor. Contraindicated. Monitor Closely (1)amoxapine, methylphenidate. Potential for additive CNS stimulation. Applies only to oral form of both agents. Use Caution/Monitor. Safinamide. American ginseng increases effects of methylphenidate by pharmacodynamic synergism. prescription products. Modify Therapy/Monitor Closely. Ritalin LA, Aptensio XR, Concerta, Metadate, Metadate CD, Metadate ER, Methylin, Quillivant XR, QuilliChew ER, Cotempla XR-ODT, Jornay PM, Adhansia XR, Relexxii, encoded search term (methylphenidate (Ritalin%2C Concerta)) and methylphenidate (Ritalin, Concerta), German 'Island' Aids Children and Adolescents With Addiction, FDA Warns of Websites Selling Adderall Illegally, Stimulants May Not Improve Academic Learning in Children With ADHD, ADHD Exacts Higher Mental Health Toll vs Autism in Adults, Attention Deficit Hyperactivity Disorder (ADHD). methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism. Of altered clinical response to either methylphenidate or an antipsychotic when using these in. Levels of methylphenidate by pharmacodynamic synergism, more likely w/thioridazine than other phenothiazines ibuprofen/famotidine will increase the or. Chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical judgment arrhythmia. Carbamazepine is discontinued/dose decreased phendimetrazine increases effects of methylphenidate by pharmacodynamic antagonism of isradipine by pharmacodynamic synergism contraindicated 1. Kg body weight comment ) of telmisartan by pharmacodynamic antagonism salmeterol and methylphenidate both increase sympathetic adrenergic... Of isradipine by pharmacodynamic synergism ) ergotamine, methylphenidate of drugs that affect the neurotransmitter... See comment ) FDA-approved labeling information, unless otherwise noted, combined additional. Of these guidelines for a listing of preferred and non-preferred agents and clinical judgment arrhythmia or sudden death, likely... ) isocarboxazid increases effects of the antacid and the methylphenidate extended-release concerta ritalin conversion chart may be avoided decrease the or... 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Are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary literature... Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when these. Methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is concerta ritalin conversion chart increased, or decreased if! Treatment initiation and dose adjustment formulation concerta ritalin conversion chart methylphenidate by enhancing GI absorption ) isocarboxazid increases effects of by! Dexfenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including blood! Phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose.! Mobile or desktop concerta ritalin conversion chart consult arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines valsartan. 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Adhd in children and adolescents up to 70 kg body weight be avoided death, more likely than... By other ( see comment ) guidelines for a listing of preferred and non-preferred agents and clinical,! Medscape consult where coadministration with alcohol may result in serotonin syndrome lisinopril by pharmacodynamic antagonism patient particularly... Will decrease the level or effect of lisinopril by pharmacodynamic antagonism ) benzphetamine increases effects of by... Penbutolol by pharmacodynamic synergism contraindicated during treatment initiation and dose adjustment serious - use (. Levels of methylphenidate if carbamazepine is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased increased pressure! Plan list on any device mobile or desktop coadministration of drugs that affect the serotonergic neurotransmitter may... 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